Diagnosis and Treatment of Coronary Heart Disease in Women

analysis on four major themes related to coronary heart disease (CHD) in women …… Diabetes: Study characteristics of coronary heart disease risk in ….

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Diagnosis and Treatment of Coronary Heart Disease in Women, Contents

  • Summary …1
  • Evidence Report…9
  • Chapter 1. Introduction… 11
  • Organization … 11
  • Key Questions… 12
  • References for Introduction… 15
  • Chapter 2. Systematic Review of the Accuracy of Exercise Myocardial Perfusion Imaging and Echocardiography for Diagnosis of Coronary Heart Disease in Women… 17
  • Introduction… 17
  • Methodology… 18
  • Data Sources … 18
  • Search Terms … 18
  • Inclusion Criteria … 19
  • Article Identification… 19
  • Obtaining Unpublished Results … 20
  • Quality Assessment … 20
  • Data Abstraction… 21
  • Data Management and Archive … 21
  • Data Analysis … 22
  • Results… 22
  • Study Identification … 22
  • Description of Eligible Studies … 22
  • Findings … 23
  • Conclusions … 26
  • Future Research … 28
  • References… 29
  • Chapter 3. Systematic Review of Lipid Lowering Treatment to Reduce Risk of Coronary Heart Disease in Women … 35
  • Introduction… 35
  • Methodology… 36
  • Data Sources … 36
  • Search Terms … 36
  • Inclusion Criteria … 36
  • Article Identification… 37
  • Obtaining Unpublished Results … 37
  • Quality Assessment … 37
  • Data Abstraction… 38
  • Data Management and Archive … 38
  • Data Analysis … 38
  • Results… 39
  • Results of Study Identification … 39
  • Description of Eligible Studies … 39
  • Findings … 40
  • Conclusions … 43
  • Future Research … 45
  • References… 47
  • Chapter 4. Systematic Review of Diabetes as a Risk Factor for Coronary Heart Disease in Women… 51
  • Introduction… 51
  • Methodology… 51
  • Data Sources … 51
  • Search Terms … 52
  • Inclusion Criteria … 52
  • Definition of Outcomes … 52
  • Article Identification… 52
  • Obtaining Unpublished Results in Women… 53
  • Quality Assessment … 53
  • Data Abstraction… 54
  • Data Management and Archive … 54
  • Data Analysis … 54
  • Results… 55
  • Results of Study Identification … 55
  • Description of Eligible Studies … 56
  • Summary of Results… 56
  • Conclusions … 57
  • Future Research … 59
  • References… 61
  • Chapter 5. Systematic Review of Troponin as a Prognostic Factor for CHD in Women… 67
  • Introduction… 67
  • Methodology… 68
  • Data Sources … 68
  • Search Terms … 68
  • Inclusion and Exclusion Criteria … 69
  • Article Identification… 69
  • Data Abstraction… 69
  • Obtaining Unpublished Results … 69
  • Quality Assessment … 69
  • Data Management and Archive … 69
  • Data Analysis … 70
  • Results… 70
  • Results of Study Identification … 70
  • Patient Characteristics … 71
  • Study Report Characteristics … 71
  • Quality of Study Reports … 71
  • Findings … 71
  • Conclusions … 73
  • Future Research … 74
  • References… 75

Evidence Tables … 89

  1. 1. Diagnostic Testing: Characteristics of studies of exercise myocardial perfusion imaging… 91
  2. 2. Diagnostic Testing: Characteristics of studies of exercise echocardiography… 92
  3. 3. Diagnostic Testing: Findings of exercise myocardial perfusion imaging and summary estimates of accuracy… 93
  4. 4. Diagnostic Testing: Summary estimates of accuracy of myocardial perfusion imaging from studies using sestamibi compared to studies using thallium… 95
  5. 5. Diagnostic Testing: Findings of studies of exercise echocardiography and summary estimates of accuracy … 96
  6. 6. Lipids: Characteristics of included trials … 97
  7. 7. Lipids: Outcomes of eligible studies … 99
  8. 8. Lipids: Summary results … 100
  9. 9. Diabetes: Characteristics of studies of coronary heart disease risk in diabetics vs. nondiabetics… 101
  10. 10. Diabetes: Adjusted odds ratios for CHD mortality, nonfatal MI, and all-cause mortality by sex… 103
  11. 11. Diabetes: Summary odds ratios for CHD mortality, nonfatal myocardial infarction, and all-cause mortality by sex… 104
  12. 12. Diabetes: Summary odds ratios for CHD mortality by sex, quality of studies and sensitivity analysis… 105
  13. 13. Troponin: Characteristics of the study population by gender … 106
  14. 14. Troponin: Characteristics of the study reports… 107
  15. 15. Troponin: Outcomes for women… 108
  16. 16. Troponin: Outcomes for men… 109

Bibliography … 111
Appendixes … 125

  • A. Peer Reviewers… 127
  • B. Quality Evaluation Forms … 131
  • C. Data Abstraction Forms … 137
  • D. Abbreviations and Acronyms… 157

Figures:

  1. Troponin: Death for women with and without an elevated troponin… 79
  2. Troponin: Death for men with and without an elevated troponin… 80
  3. Troponin: Death or myocardial infarction for women with and without an elevated troponin … 81
  4. Troponin: Death or myocardial infarction for men with and without an elevated troponin … 82
  5. Troponin: Nonfatal infarction for women with and without an elevated troponin … 83
  6. Troponin: Nonfatal infarction for men with and without an elevated troponin… 84
  7. Troponin: Odds ratios and their summary for death for both men and women… 85
  8. Troponin: Odds ratios and their summary for death or myocardial infarction for both men and women… 86
  9. Troponin: Odds ratios and their summary for nonfatal myocardial infarction for both men and women… 87

 

Download Diagnosis and Treatment of Coronary Heart Disease in Women pdf from www.ahrq.gov, 144 pages, 541.68KB.
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