Guidlines on Testicular Cancer

Staging is the cornerstone on which the treatment of testicular cancer is based. …… Breast cancer staging in testis: imaging modality selection ….

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GUIDELINES ON TESTICULAR CANCER:
BACKGROUND

  • Methods

PATHOLOGY AND NATURAL HISTORY
DIAGNOSIS

  • Clinical examination
  • Imaging of the Testis
  • Serum Tumor Markers at diagnostic
  • Inguinal exploration and orchiectomy
  • Organ sparing surgery
  • Pathological examination of the testis
  • Diagnosis of Carcinoma in situ (Tin)
  • Screening

STAGING

  • Diagnostic tools
  • Serum tumour markers. Postorchiectomy half-life kinetics
  • Abdominal, mediastinal, supraclavicular nodes and viscera
  • Staging and prognostic classifications
  • Prognostic risk factors

IMPACT ON FERTILITY AND FERTILITY ASSOCIATED ISSUES
GUIDELINES ON DIAGNOSIS AND STAGING OF TESTICULAR CANCER

  • References (Diagnosis and Staging testis tumor)
  • TREATMENT: STAGE I GERM CELL TUMOURS
  • Stage I seminoma
  • Guidelines for the treatment of seminoma stage I
  • NSGCT stage I
  • CS1S with (persistently) elevated serum tumour markers
  • Guidelines on the treatment of NSGCT stage I
  • References (Treatment Stage I Testis Tumor)

TREATMENT: METASTATIC GERM CELL TUMOURS

  • Primary chemotherapy
  • Restaging and further treatment
  • Systemic Salvage treatment for relapse or refractory disease
  • Salvage Surgery
  • Treatment of brain metastases
  • Guidelines for the treatment of metastatic germ cell tumours
  • References (Treatment of Metastatic disease)

FOLLOW-UP AFTER CURATIVE THERAPY

  • General considerations
  • References (General considerations)
  • Follow-up stage I Non-seminoma
  • References (Follow-up Stage I Nonseminoma)
  • Follow-up: stage I Seminoma
  • References (Follow-up stage I Seminoma)
  • Follow-up stage II and advanced (metastatic) disease
  • References (Follow-up advanced disease)

ABBREVIATIONS

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