Alzheimer’€™s Disease Unraveling the Mystery

Alzheimer’s disease Genetics of late-onset Alzheimer’s …… may cause malfunction of cells and possibly disease. ….

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Alzheimer’s Disease Unraveling the Mystery
Introduction …4
The Impact of Alzheimer’s Disease …6
Unraveling the Mystery …8
Part 1: A Walking Tour Through the Brain …10
Inside the Human Brain …11
Neurons and Their Jobs …16
Plaques and Tangles: The Hallmarks of AD …20
The Changing Brain in Alzheimer’s Disease …24
Part 2: AD Research – Finding New Answers and Asking Better Questions …30
The Search for Causes …31
Genetic Factors at Work in AD …31
Genes and Early-onset Alzheimer’s Disease …33
A Different Genetic Story in Late-onset Alzheimer’s Disease …33
Other Factors at Work in AD …34
Beta-amyloid …34
Tau …35
Cardiovascular Risk Factors …35
Oxidative Damage from Free Radicals …36
Inflammation …36
Brain Infarction …36
New Techniques Help in Diagnosing AD …37
The Search for New Treatments …42
Helping People with AD Maintain Their Mental Functioning …42
Slowing, Delaying, or Preventing Alzheimer’s Disease …43
Managing Symptoms …45
Improving Support for Families and Other Caregivers …49
Glossary …54
For More Information …57

Download Alzheimer'€™s Disease Unraveling the Mystery pdf from www.nia.nih.gov, 65 pages, 7657.79KB.
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