Guidelines on Renal Cell Carcinoma

about 30000 patients were diagnosed with kidney cancer within the EU and approximately 15000 died of the disease (4). Renal cell carcinoma is the most …

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Guidelines on Renal Cell Carcinoma
B. Ljungberg, D.C. Hanbury, M.A. Kuczyk, A.S. Merseburger, P.F.A. Mulders, J-J. Patard, I.C. Sinescu
INTRODUCTION
BACKGROUND: EPIDEMIOLOGY AND AETIOLOGY
2.1 Conclusion
2.2 Recommendation
2.3 References
DIAGNOSIS AND STAGING
3.1 Symptoms
3.1.1 Physical examination
3.1.2 Laboratory findings
3.2 Radiological investigations
3.3 Conclusion
3.4 Recommendation
3.5 References
CLASSIFICATION AND PROGNOSTIC FACTORS
4.1 Classification
4.2 Prognostic factors
4.2.1 Anatomical factors
4.2.2 Histological factors
4.2.3 Clinical factors
4.2.4 Molecular factors
4.2.5 Prognostic systems and nomograms
4.3 Conclusion
4.4 Recommendations for classification and prognosis
4.5 References
TREATMENT OF LOCALIZED DISEASE
5.1 Surgery
5.1.1 Embolization
5.1.1.1 Conclusion
5.1.1.2 Recommendation
5.1.2 Nephron-sparing surgery
5.1.2.1 Conclusion
5.1.2.2 Recommendation
5.1.3 Laparoscopic nephrectomy
5.1.3.1 Conclusion
5.1.3.2 Recommendation
5.1.4 Partial laparoscopic nephrectomy
5.1.4.1 Conclusion
5.1.4.2 Recommendation
5.2 Alternative treatment
5.2.1 Conclusion
5.2.2 Recommendation
5.3 Adjuvant therapy
5.3.1 Conclusion
5.3.2 Recommendation
5.4 Surgical treatment of metastatic RCC (tumour nephrectomy)
5.4.1 Conclusion
5.4.2 Recommendation
5.5 Resection of metastases
5.5.1 Conclusion
5.5.2 Recommendation
5.6 Radiotherapy for metastases in RCC
5.6.1 Conclusion
5.6.2 Recommendation
5.7 References
SYSTEMIC THERAPY FOR METASTATIC RCC
6.1 Chemotherapy
6.1.1 Conclusion
6.1.2 Recommendation
6.2 Immunotherapy
6.2.1 Interferon-alpha
6.2.1.1 Conclusion
6.2.2 Interleukin-2
6.2.2.1 Conclusion
6.2.3 Combinations of cytokines
6.2.3.1 Conclusion
6.2.4 Recommendations
6.3 Angiogenesis inhibitor drugs
6.3.1 Sorafenib
6.3.2 Sunitinib
6.3.3 New drugs
6.3.4 Conclusion
6.3.5 Recommendations
6.4 References
SURVEILLANCE FOLLOWING RADICAL SURGERY FOR RCC
7.1 Introduction
7.2 Which investigations for which patient, and when?
7.3 Imaging modalities
7.4 Conclusion
7.5 Recommendation
7.6 References
ABBREVIATIONS USED IN THE TEXT

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