Sickle Cell Anemia: A Case Study Approach to Teaching High School Genetics

Sickle Cell Anemia and Genetics: Background Information. ¥ Sickle Cell Anemia: Blood Video Questions and Translation Practice. Worksheet …

More PDF Content

Sickle Cell Anemia: A Case Study Approach to Teaching High School Genetics
Summary: Sickle cell anemia is an example of a genetic disease that can serve as a vehicle for teaching many biology concepts. Using a case study approach, opportunities arise to make connections not only to various aspects of genetics and molecular biology, but to physiology, evolution, and societal and ethical issues as well.

Sickle Cell Anemia: Blood Video Questions and Translation Practice Worksheet Blood video/Sickle Cell Background After watching the video Blood is Life and reading the handout Sickle Cell Anemia and Genetics:
Background Information, answer the following questions.

  1. Rosalyn has sickle cell anemia. Describe her symptoms.
  2. Describe the structure of hemoglobin. (How many chains are there? What types? Why is iron necessary for blood?)
  3. How does sickle hemoglobin differ from normal hemoglobin?

Allele Frequencies and Sickle Cell Anemia Lab
Student Instructions
Objective: To observe how selective forces can change allele frequencies in a population and cause evolution to occur.
Background: Read the background information provided in the handout, Sickle Cell Anemia and Genetics: Background Information.
Introduction: Allele frequency refers to how often an allele occurs in a population. Allele frequencies can change in a population over time, depending on the `selective forces’ shaping that population. Predation, food availability, and disease are all examples of selective forces.
Evolution occurs when allele frequencies cange in a population!
In this activity, red and white beans are used to represent two alleles of globin. The RED beans represent gametes carrying the globin A allele, and the WHITE beans represent gametes carrying the globin S allele. The Gene Pool exists in a region of Africa that is infested with malaria. You are simulating the effects of a high frequency of malaria on the allele frequencies of a population.
Materials:
75 red beans, 25 white beans, 5 containers (e.g. paper cups)
Hypothesis/Prediction:
What do you think will happen to the frequencies of the A and S alleles as a result of the presence of malaria? (Will the frequency of A increase or decrease? What about S?) Formulate a hypothesis and corresponding prediction. Be sure to explain your reasoning.
Procedure:

  1. Together with your lab partner, obtain five containers and label them as follows:
    1. AA
    2. AS
    3. SS
    4. Non-surviving alleles
    5. Gene Pool
  2. Place the 75 red and 25 white beans in the Gene Pool container and mix the beans up.
  3. Simulate fertilization by PICKING OUT two `alleles’ (beans) WITHOUT LOOKING.
  4. For every two beans that are chosen from the gene pool, another person will FLIP A COIN to determine whether that individual is infected with malaria.
  5. Using the table below, the coin flipper tells the bean picker in which containers to put the beans.

sickle cell anemia, Cell Anemia Lab, GTG CAC CTG, allele frequencies, Sickle Cell Hemoglobin, Cell Anemia Case, CTG ACT CCT, CAC CTG ACT, Sickle Cell Disease, Case Study, TOTAL SURVIVING ALLELES, Analysis, amino acid, Cell Background, Genetics, Practice Worksheet, Restriction Analysis, CCT GTG GAG, Questions, ACT CCT GAG, Student Instructions, DNA Restriction Analysis, Class Results, restriction enzyme mst, High School Genetics, Blood Video Questions, Translation Practice Worksheet, Case Study Approach, Normal Beta Chain, family 1 key, Class Results Table, Genetics Concepts, Diagnosis Lab, Instructional Materials, Grade Level, Background Information, Summary, Molecular Biology, Molecular Level, Classroom Activities, PreLab Questions, Current Research, selective forces, Overhead Master, Class Totals, Extension Ideas, PreLab Reading, Data Sheet, recognition site, Diagnostic Tool

Download Sickle Cell Anemia: A Case Study Approach to Teaching High School Genetics pdf from genetics-education-partnership.mbt.washington.edu, 21 pages, 78.21KB.

5 Responses to “Sickle Cell Anemia: A Case Study Approach to Teaching High School Genetics”

  1. I all the time used to read paragraph in news papers but now
    as I am a user of internet so from now I am using net for articles,
    thanks to web.

  2. Hi, i think that i saw you visited my blog so i came to “return the favor”.
    I’m trying to find things to enhance my website!I suppose its ok to use a few of your ideas!!

  3. chanyuan11.21 ugg boots michael kors outlet online hollister canada cheap mlb jerseys coach outlet online vans shoes christian louboutin uk coach factory outlet online air jordan 13 salomon shoes asics ray ban sunglasses michael kors outlet ed hardy clothing canada goose outlet canada goose jackets toms shoes louis vuitton outlet longchamp handbags coach outlet clearance polo ralph lauren canada goose jackets swarovski crystal ray ban sunglasses ferragamo shoes cheap nba jerseys longchamp outlet nike outlet store nike air max nike foamposite the north face jackets ugg boots true religion jeans versace sunglasses michael kors outlet oakley sunglasses fitflops sale clearance canada goose juicy couture outlet ray ban sunglasses sale michael kors outlet ferragamo outlet hollister clothing cheap jordans for sale kobe shoes chrome hearts air jordan shoes rolex watches michael kors factory outlet coach outlet louis vuitton kobe bryant shoes tory burch shoes michael kors outlet clearance longchamp bag louis vuitton sunglasses coach outlet clearance oakley sunglasses wholesale cheap jordans ugg boots chrome hearts outlet burberry outlet ray ban sunglasses coach factory outlet michael kors handbags mulberry handbags moncler outlet cheap nfl jerseys beats by dr dre nike roshe run adidas wings canada goose outlet michael kors wallets for women michael kors outlet clearance chrome hearts outlet ugg boots longchamp pliage north face jackets louis vuitton handbags swarovski crystal sac longchamp adidas outlet store ray ban sunglasses hermes birkin nike outlet true religion outlet true religion jeans burberry outlet ugg boots marc jacobs outlet swarovski crystal ugg outlet longchamp outlet mulberry handbags oakley sunglasses louis vuitton neverfull canada goose jackets christian louboutin online jordan shoes air max uk canada goose outlet michael kors handbags ugg boots soccer jerseys the north face jackets ugg outlet louis vuitton handbags ysl outlet canada goose outlet louis vuitton handbags coach outlet michael kors outlet clearance canada goose jackets prada shoes coach outlet store online kobe 9 canada goose outlet valentino outlet michael kors outlet canada goose jackets coach outlet coach outlet oakley sunglasses kate spade handbags puma outlet nike roshe longchamp pas cher louis vuitton giuseppe zanotti outlet louis vuitton outlet coach outlet online louis vuitton louboutin pas cher cheap uggs tory burch outlet nike air max 2015 converse shoes hollister sale cheap mlb jerseys reebok trainers the north face jackets rolex watches uggs outlet louis vuitton outlet ugg uk hollister uk ugg boots louis vuitton outlet stores coach outlet canada ugg uk longchamp handbags michael kors outlet clearance ralph lauren canada goose outlet fitflops sale nike roshe run north face outlet michael kors uk coach outlet online uggs outlet ralph lauren pas cher michael kors outlet coach outlet online canada goose outlet oakley sunglasses coach outlet true religion jeans coach outlet air max 90 michael kors outlet store nike outlet store nike free running montblanc pens rolex outlet air max 90 coach outlet online nike free 5 tory burch outlet ralph lauren uk ugg canada louis vuitton ugg boots louis vuitton handbags coach outlet prada handbags michael kors outlet michael kors factory outlet oakley sunglasses wholesale omega watches canada goose jackets coach outlet lacoste polo shirts mulberry sale michael kors handbags michael kors outlet store rolex watches cartier watches lacoste pas cher ralph lauren uk snow boots cartier watches snow boots for women ugg outlet ugg outlet louis vuitton uk uggs on sale coach outlet online air jordan 4 nike air force 1 michael kors outlet louis vuitton handbags michael kors wallets north face jackets hermes bags replica watches nike store uk canada goose outlet ugg slippers michael kors outlet clearance tiffany and co jewelry adidas uk lululemon outlet toms shoes instyler ionic styler nike mercurial fitflops sale ray-ban sunglasses ralph lauren polo shirts fitflops outlet beats by dre polo ralph lauren true religion outlet ralph lauren pas cher fitflops sale polo ralph lauren ugg outlet michael kors handbags clearance uggs outlet nike tn pas cher gucci outlet tory burch outlet north face jackets ralph lauren shirts louis vuitton handbags hollister clothing canada goose outlet uggs outlet louis vuitton pas cher coach handbags chaussure louboutin tods outlet nike huarache louis vuitton outlet stores louis vuitton outlet rolex watches for sale ugg outlet thomas sabo uk cheap jordans christian louboutin outlet canada goose outlet prada outlet nike free run ugg boots uk true religion jeans ugg outlet coach outlet clearance fitflops sale clearance cheap uggs ferragamo shoes hollister uk louis vuitton bags bottega veneta outlet mulberry outlet michael kors outlet clearance true religion jeans fitflops shoes north face outlet swarovski uk true religion jeans canada goose outlet lululemon outlet celine outlet north face jackets air max uk cheap snapbacks chrome hearts coach outlet michael kors handbags ugg outlet clearance michael kors outlet clearance coach outlet canada goose jackets uggs outlet mcm outlet ugg outlet ugg boots timberland boots michael kors outlet basketball shoes cheap jordans free shipping longchamp handbags hermes belt uggs outlet oakley sunglasses air jordan 11 michael kors factory outlet ugg boots oakley sunglasses abercrombie and fitch ugg outlet tory burch outlet iphone case longchamp handbag mbt shoes hermes outlet cheap nike shoes ralph lauren polo louis vuitton outlet coach outlet clearance coach outlet store online true religion jeans coach outlet air max 90 nba jerseys links of london michael kors handbags michael kors outlet online ugg outlet oakley sunglasses true religion jeans mizuno running shoes ferragamo shoes dior sunglasses north face outlet tiffany and co longchamp outlet michael kors outlet michael kors handbags polo ralph lauren louis vuitton canada goose jackets nike air max uk nike trainers burberry outlet louis vuitton coach factory outlet north face jackets herve leger outlet louis vuitton handbags coach outlet coach outlet online north face uk michael kors outlet christian louboutin outlet canada goose outlet longchamp pliage canada goose outlet nfl jerseys wholesale true religion jeans nike air force 1 michael kors outlet online christian louboutin outlet swarovski crystal canada goose jackets canada goose jackets cheap nhl jerseys rolex watches yeezy boost tory burch outlet adidas nmd true religion sale oakley sunglasses longchamp solde michael kors outlet tiffany jewellery reebok outlet store oakley sunglasses nike blazer pas cher mulberry handbags ferragamo outlet cheap jordans canada goose outlet cheap uggs cazal sunglasses ray ban wayfarer supra shoes kate spade handbags polo ralph lauren the north face outlet air max uk toms shoes louis vuitton pas cher ray ban sunglasses swarovski crystal michael kors outlet fred perry polo shirts uggs canada adidas trainers michael kors handbags coach factory outlet polo ralph lauren michael kors outlet louis vuitton outlet ray ban sunglasses futbol baratas canada goose jackets ralph lauren polo canada goose outlet michael kors canada louis vuitton outlet stores rolex watches mont blanc pens ralph lauren polo uggs outlet abercrombie and fitch lebron james shoes beats by dr dre michael kors outlet clearance ugg uk fitflop clearance coach outlet online yeezy boost 350 moncler coats jordan shoes mulberry handbags polo ralph lauren true religion outlet mulberry bags lululemon outlet michael kors outlet clearance michael kors bags cartier watches moncler outlet online prada sunglasses michael kors outlet online pandora jewelry cartier outlet louis vuitton rolex watches air max 90 fitflops shoes cartier watches football shirts lebron james shoes north face jackets ghd hair straighteners north face jackets cheap jordans michael kors handbags mac cosmetics moncler jackets michael kors outlet michael kors handbags cheap michael kors handbags outlet nike free run canada goose jackets the north face jackets cheap nfl jerseys soccer jerseys louis vuitton michael kors factory outlet ugg sale ugg outlet toms shoes canada goose jackets ugg outlet uk replica watches air max 90 ferragamo shoes beats headphones swarovski jewelry true religion outlet jordan pas cher celine outlet tiffany jewellery true religion uk mulberry outlet new balance shoes coach outlet nike huarache coach outlet online ferragamo outlet ugg boots ralph lauren uk uggs pandora jewelry moncler outlet adidas nmd runner

  4. detroit lions jerseys chicago bulls jersey oakley sunglasses michael kors handbags moncler outlet converse trainers adidas nmd michael kors handbags true religion jeans pittsburgh steelers jersey new england patriots jerseys michael kors handbags atlanta falcons jersey los angeles clippers jerseys seattle seahawks jerseys salomon shoes ed hardy uk chargers jerseys kansas city chiefs jerseys michael kors outlet michael kors uk nhl jerseys nike trainers michael kors outlet cincinnati bengals jerseys nike tn pas cher yeezy boost 350 michael kors handbags versace shoes michael kors handbags gucci borse jacksonville jaguars jersey lebron james shoes christian louboutin outlet michael kors new york giants jerseys pandora charms michael kors outlet nike store new orleans saints jerseys michael kors handbags louis vuitton pas cher michael kors outlet san antonio spurs jerseys houston texans jerseys cleveland cavaliers jersey cheap jordans nike blazer pas cher oakland raiders jerseys michael kors handbags indianapolis colts jerseys basketball shoes minnesota vikings jerseys new york knicks jersey longchamps instyler max baltimore ravens jerseys ed hardy cleveland browns jerseys kobe 9 elite new balance shoes buffalo bills jerseys michael kors handbags sac longchamp nike outlet hugo boss sale chaussure louboutin pas cher valentino shoes tennessee titans jersey armani exchange jordan shoes nike huarache michael kors handbags nike roshe replica watches green bay packers jerseys polo ralph lauren oklahoma city thunder jerseys san francisco 49ers jerseys miami heat jersey reebok outlet arizona cardinals jerseys adidas nmd michael kors handbags supra shoes mont blanc pens michael kors handbags abercrombie and fitch nba jerseys denver broncos jerseys ferragamo shoes omega watches michael kors handbags michael kors handbags golden state warriors jerseys fitflops michael kors outlet boston celtics jersey carolina panthers jersey ray ban sunglasses michael kors handbags jordan shoes cheap nike shoes nike air force 1 michael kors outlet saics running shoes ghd flat iron ecco shoes nike air huarache mlb jerseys michael kors outlet polo ralph lauren outlet los angeles lakers jerseys new york jets jerseys michael kors handbags philadelphia eagles jerseys ray ban sunglasses michael kors outlet nike trainers the north face oakley sunglasses miami dolphins jerseys birkenstock sandals nike free chicago bears jerseys cheap nfl jerseys tiffany and co washington redskins jerseys oakley sunglasses michael kors handbags under armour outlet nike air huarache toms shoes pandora jewelry ralph lauren pas cher fitflops shoes dallas cowboys jersey nike blazer pas cher air max 90 dolce and gabbana skechers outlet michael kors handbags jimmy choo michael kors handbags

  5. 20170421 xushengda on April 21st, 2017 at 2:35 am

    coach factory outlet coach outlet online louboutin shoes air max 90 adidas nmd runner adidas yeezy boost birkenstock uk fit flops coach handbags outlet coach outlet online polo ralph lauren outlet coach outlet canada christian louboutin outlet louis vuitton outlet store adidas nmd r1 yankees jerseys mbt longchamp sale ed hardy uk cheap oakley sunglasses nike uk pandora charms sale clearance michael kors outlet online cheap air max ray ban sale moncler jackets birkenstock coach factory outlet online pandora charms coach factory outlet online michael kors fitflops sale clearance coach factory outlet online michael kors bags michael kors longchamp soldes longchamp handbags mulberry outlet uk coach outlet online pandora charms outlet fitflops clearance pandora jewelry dodgers jerseys polo ralph lauren yeezy boost 350 ray ban glasses swarovski sale bulls jerseys louboutin shoes yeezy shoes toms shoes red bottom shoes for women nike free run coach factory outlet gucci bags louboutin outlet christian louboutin shoes michael kors pandora jewellery valentino outlet oakley sunglasses wholesale cheap jordan shoes fitflops sale celine handbags longchamps coach factory outlet store coach outlet online christian louboutin sale louis vuitton outlet online polo ralph lauren moncler coats mlb jerseys pandora charms chaussure louboutin pas cher fendi bags hollister clothing michael kors outlet clearance michael kors nike air huarache longchamp handbags ray bans coach factory outlet online burberry outlet discount oakley sunglasses nike free run flyknit ralph lauren louis vuitton factory outlet christian louboutin mulberry bags coach outlet online air max 90 parada bags dansko outlet mulberry handbags adidas sneakers birkenstock outlet polo ralph lauren outlet online moncler pas cher pandora charms fitflops yeezy boost ghd straighteners sale oakley sunglasses cheap longchamp bag vans outlet coach outlet store nike roshe one mulberry uk michael kors outlet store toms fitflops coach outlet online coach outlet store red bottom heels michael kors outlet store tods shoes timberland boots outle adidas nmd runner tommy hilfiger windbreaker coach outlet store online red sox jerseys michael kors outlet store cheap oakley sunglasses packers jerseys cheap ray ban sunglasses ralph lauren outlet cheap jordan shoes tigers jerseys discount oakley sunglasses burberry sale true religion outlet store ralph lauren outlet online cubs jerseys pandora charms outlet polo ralph lauren outlet online eahawks jerseys cheap nfl jerseys michael kors outlet online coach factory outlet online louis vuitton purses pandora yeezy boost 350 true religion uk michael kors outlet online james shoes coach outlet store online ed hardy outlet nike outlet swarovski uk air max nike flyknit toms coach factory outlet online discount oakley sunglasses thunder jerseys coach factory outlet beats headphones adidas trainers cheap jordan shoes hollister clothing store rangers jerseys mlb jerseys true religion jeans outlet ralph lauren sale jimmy choo shoes fitflop air jordans mbt ralph lauren outlet coach outlet store polo ralph lauren coach outlet online michael kors outlet store air jordans pandora uk coach factory outlet cheap jerseys louis vuitton outlet online michael kors outlet online nmd adidas michael kors birkenstock outlet lakers jerseys michael kors outlet canada prada outlet online burberry outlet online true religion jeans outlet beats by dre coach factory outlet online ray ban sunglasses discount pandora jewelry ray ban sunglasses outlet polo ralph lauren pas cher michael kors outlet clearance christian louboutin outlet jordan retro coach outlet online michael kors bags pandora charms sale clearance birkenstock shoes adidas nmd r1 jordan femmes pas cher ghd hair gucci handbags outlet nike roshe shoes oakley sunglasses outlet coach factory outlet online bercrombie nfl jerseys wholesale cheap oakley sunglasses gucci handbags outlet adidas outlet online fitflop nike outlet store toms ralph lauren outlet pandora jewelry store adidas outlet store coach outlet online adidas fit flops nike blazer low pas cher toms outlet store 49ers jerseys ralph lauren uk polo ralph lauren outlet online kobe bryant shoes adidas trainers harden shoes michael kors purses air max 90 nike sneakers chaussures louboutin adidas uk gucci outlet online birkenstock outlet cowboys jerseys michael kors outlet michael kors outlet clearance kate spade outlet online warriors jerseys michael kors outlet store adidas nmd r1 sac longchamp air max sac longchamp fred perry shirts michael kors purs jerseys pandora charms outlet dolce and gabbana outlet online hermes outlet online louis vuitton fitflops clearance kate spade uk rolex watches ralph lauren outlet online coach outlet online louboutin outlet ray ban glasses swarovski crystals nike outlet store adidas superstar trainers sac louis vuitton polo ralph lauren michael kors louis vuitton handbags michael kors outlet online toms outlet birkin handbags red bottom air max kate spade outlet online chaussures louboutin adidas running shoes nike air force coach outlet store coach factory outlet online mulberry adidas sneakers marc jacobs outlet patriots jerseys pandora jewellery coach factory outlet online adidas yeezy boost nike cortez classic gucci true religion longchamp bags michael kors outlet online ralph lauren sale clearance uk cheap nike sneakers louis vuitton outlet store ralph lauren coach outlet store online birkenstocks mulberry uk kate spade bags cheap oakley sunglasses kate spade handbags longchamp handbags michael kors outlet clearance kate spade bags hollister kids hermes bag coach factory outlet online adidas outlet store yeezy boost true religion sale cheap nike shoes white sox jerseys coach purses christian louboutin shoes polo ralph lauren outlet cheap oakley sunglasses michael kors outlet clearance michael kors outlet canada levis outlet ralph lauren outlet online true religion jeans michael kors bags nike air max kd shoes coach outlet online yeezy boost 350 gucci bags adidas superstar shoes christian louboutin cheap ray ban sunglasses hermes bags ralph lauren outlet pandora outlet moncler uk louboutin pas cher rolex watches rolex replica watches louis vuitton outlet online ed hardy clothing discount oakley sunglasses phillies jerseys polo ralph lauren outlet online oakley sunglasses outlet ralph lauren christian louboutin pas cher polo ralph lauren outlet online cheap jordan shoes cheap rolex replica watches ralph lauren sale michael kors outlet online nike outlet online pandora jewelry outlet longchamp pliage fitflops sale wireless beats headphones rolex replica watches for sale coach outlet store online coach outlet coach factory outlet online hermes bags ray ban sunglasses sale jerseys cheap coach outlet online curry shoes tory burch outlet online cheap air jordans michael kors outlet store moncler jackets pandora jewelry outlet versace cheap rolex watches texans jerseys gucci outlet online yeezy boost 350 burberry outlet store ralph lauren outlet online adidas ultra boost lebron shoes longchamp outlet store adidas yeezy boost 350 ralph lauren sale longchamp bag nike outlet nike air max 95 fred perry polo shirts christian louboutin outlet beats wireless headphones adidas nmd r1 cheap jordans for sale ed hardy store hermes outlet air max shoes michael kors uk nike outlet store ray ban sunglasses outlet rolex replica watches for sale kate spade outlet online giants jerseys broncos jerseys rockets jerseys nfl jerseys cheap nike free 4.0 flyknit cavaliers jerseys michael kors outlet online fitflop shoes adidas nmd runner marc jacobs polo ralph lauren outlet toms outlet sac louis vuitton pas cher gucci borse fitflops sale ralph lauren sale michael kors handbags outlet coach factory outlet online vans store true religion outlet store cheap oakley sunglasses michael kors handbags outlet christian louboutin uk oakley sunglasses outlet christian louboutin outlet mont blanc pen coach factory outlet oakley sunglasses on sale michael kors outlet louboutin shoes michael kors polo ralph lauren outlet online nfl jerseys wholesale pandora charms sale coach outlet store online louis vuitton bags nfl jerseys fitflop shoes dansko coach outlet online coach factory outlet ray ban sunglasses discount jordan shoes montblanc fitflops sale clearance coach factory outlet michael kors handbags nike sneakers heat jerseys louis vuitton outlet online coach outlet online coach outlet online adidas store adidas sneakers mlb jerseys cheap jordan shoes kd 8 shoes michael kors outlet clearance coach outlet online michael kors yeezy 350 boost fake rolex watches coach outlet online moncler outlet online tory burch sale louis vuitton factory outlet yeezy boost polo ralph lauren outlet michael kors outlet online coach outlet store michael kors outlet store pandora charms kate spade outlet store nike store michael kors outlet online ralph lauren coach outlet online nike tn pas cher pandora charms sale oakley sunglasses outlet true religion jeans outlet coach outlet online yeezy shoes coach factory outlet online moncler uk adidas jordan shoes ray ban sunglasses cheap pandora charms sale clearance coach factory outlet online eltics jerseys ray ban sunglasses discount yeezy boost 350 v2 discount nike shoes jordan uk longchamp bags tods outlet coach factory outlet online kate spade outlet online coach outlet store online yeezy boost nike air max 95 nike outlet store online cardinals jerseys ralph lauren sale clearance uk louboutin outlet air max outlet coach outlet online true religion jeans outlet pandora charms sale clearance fit flops christian louboutin true religion jeans outlet montblanc pens longchamp bags mlb jerseys cheap oakley sunglasses coach outlet store online clearance michael kors outlet store michael kors outlet store michael kors uk coach outlet online tory burch outlet online true religion outlet online kate spade outlet michael kors outlet store adidas nmd runner birkenstocks michael kors bags mont blanc pens michael kors handbags clearance adidas outlet online ray bans cheap jerseys christian louboutin shoes kate spade louboutin outlet polo ralph lauren outlet mont blanc pen tommy hilfiger outlet red bottom burberry outlet discount oakley sunglasses adidas superstars adidas yeezy boost cheap oakley sunglasses coach outlet online discount oakley sunglasses polo ralph lauren yeezy shoes jordans fred perry polo shirts coach outlet gucci abercrombie outlet chi flat iron ralph lauren outlet online adidas superstars adidas yeezy boost air jordan shoes kate spade purses coach factory outlet celine outlet online pandora bracelet christian louboutin sale xushengda0421

Leave a Reply